GLOBAL PROTEIN CONJUGATION BY UBIQUITIN-LIKE-MODIFIERS DURING ISCHEMIC STRESS IS REGULATED BY MICRORNAS AND CONFERS ROBUST TOLERANCE TO ISCHEMIA.

Global protein conjugation by ubiquitin-like-modifiers during ischemic stress is regulated by microRNAs and confers robust tolerance to ischemia.

Hibernation torpor provides an excellent model of natural tolerance to ischemia.We have previously shown that massive global SUMOylation CARRIAGE ROLLER occurs during hibernation torpor in ground squirrels.We have also shown that overexpression of Ubc9, SUMO-1, or SUMO-2/3 provides protection against ischemic damage in cell lines and cortical neuro

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A possible role for Phlebotomus (Anaphlebotomus) rodhaini (Parrot, 1930) in transmission of Leishmania donovani

Abstract Background Visceral leishmaniasis (VL, kala azar), caused by Leishmania donovani is a major health problem in Sudan and other East African countries.In this region the only proven vectors of L.donovani are Phlebotomus orientalis in eastern Sudan, Ethiopia and Upper Nile areas of Southern Sudan and Phlebotomus martini in Ethiopia, Kenya and

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